d205 - rDer p 10 (Dermatophagoides pteronyssinus)
Test details
This test is useful when a dust mite allergy is suspected and to identify the specific molecule that has previously caused a positive result in the associated allergen extract test.
Der p 10 is a tropomyosin found in the body (muscles) of house dust mites, and its prevalence does not exceed 20% among patients sensitised to Dermatophagoides pteronyssinus. Symptoms associated with an allergy to this molecule mainly include allergic rhinitis, conjunctivitis and coughing due to an itchy throat. In some cases, the allergy may cause skin symptoms and lead to bronchial asthma.
Classified as a pan-allergen, Der p 10 can cause cross-reactions with the tropomyosins found in shellfish (shrimp, crab, lobster) and molluscs (mussels, oysters, scallops, snails, squid, cuttlefish, octopus).
Sample type
Serum
Method
ChLIA
Preparation
Fasting for at least 8-12 hours before sampling
Storage conditions
Refer to the Health Service Charter to check storage conditions
Shipping
+2/+8°C
References
Hamilton RG. Allergic sensitization is a key risk factor for but not synonymous with allergic disease. J Allergy Clin Immunol. 2014 Aug;134(2):360-1. doi: 10.1016/j.jaci.2014.02.022. Epub 2014 Mar 31. PMID: 24698318.
Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, et al. EAACI Molecular Allergology User's Guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250. doi: 10.1111/pai.12563. PMID: 27288833.
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