Allergology

f233 - nGal d 1 (Egg– Gallus domesticus)

Test details

This test is useful when an egg allergy is suspected and to identify the specific molecule that has previously caused a positive result in the associated allergen extract test.

 

Also known as ovomucoid, Gal d 1 is a protein found in egg whites and is considered one of the main allergenic protein molecules associated with allergic reactions in children. The prevalence of this molecule can exceed 40% in paediatric patients sensitised to egg. Due to its resistance to both heat and enzymatic digestion, individuals with a suspected allergy to Gal d 1 may experience gastrointestinal, skin, respiratory and mucosal reactions, and even anaphylaxis, also after the ingestion cooked egg white. Cross-reactivities may occur with the whites of turkey, duck and goose eggs.

Sample type

Serum

Method

ChLIA

Preparation

Fasting for at least 8-12 hours before sampling

Storage conditions

Refer to the Health Service Charter to check storage conditions

Shipping

+2/+8°C

References

Hamilton RG. Allergic sensitization is a key risk factor for but not synonymous with allergic disease. J Allergy Clin Immunol. 2014 Aug;134(2):360-1. doi: 10.1016/j.jaci.2014.02.022. Epub 2014 Mar 31. PMID: 24698318.

Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, et al. EAACI Molecular Allergology User's Guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250. doi: 10.1111/pai.12563. PMID: 27288833.

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