This test is useful when a mould allergy is suspected and to identify the specific molecule that has previously caused a positive result in the associated allergen extract test.
Alt a 1 is a protein mainly found in the cell wall and cytoplasm of mature spores of the mould Alternaria.
The airborne concentration of Alt a 1 presents seasonal variations depending on the local climate, with levels peaking in the summer.
Cross-reactivity is possible almost exclusively with Alt a 1 homologues in phylogenetically related fungi of the Pleosporaceae family.
The prevalence of Alt a 1 is almost 50% among patients sensitised to Alternaria spores.
Symptoms associated with an allergy to this molecule mainly include allergic rhinitis, conjunctivitis, and coughing caused an itchy throat; in some cases, the allergy may also cause skin symptoms and lead to bronchial asthma.
The assessment of sensitisation to Alt a 1 is considered important for selecting patients eligible for allergen-specific immunotherapy (AIT).
Serum
ChLIA
Fasting for at least 8-12 hours before sampling
Refer to the Health Service Charter to check storage conditions
+2/+8°C
This test provides the quantitative determination of total tau protein to support the diagnosis of Alzheimer’s disease.
This test provides the quantitative determination of tau protein phosphorylated at threonine 181 (pTau181), to support the diagnosis of Alzheimer’s disease.
Test for the determination of human autoantibodies against NMDAR to support the diagnosis of paraneoplastic neurological syndromes with an intermediate-risk phenotype.
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