Neurology

Anti–Zic4 Antibodies

Test details

Anti-Zic4 antibodies are diagnostic markers for the serological diagnosis of paraneoplastic neurological syndromes and are typically detected in the context of cerebellar degeneration. Anti-Zic4 antibodies are associated with small-cell lung carcinoma (SCLC).

Sample type

Serum, EDTA plasma, heparin plasma, citrate plasma, CSF

Method

Immunoblot

Preparation

Fasting for at least 8-12 hours before sampling

Storage conditions

Refer to the Health Service Charter to check storage conditions

Shipping

+2/+8°C

References

Ruiz-García R, Martínez-Hernández E, Saiz A, Dalmau J, Graus F. The Diagnostic Value of Onconeural Antibodies Depends on How They Are Tested. Front Immunol. 2020 Jul 14;11:1482. doi: 10.3389/fimmu.2020.01482. PMID: 32760403; PMCID: PMC7372120.

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